Combined Antiviral-Antimediator Treatment for the Common Cold
نویسندگان
چکیده
منابع مشابه
Combined antiviral-antimediator treatment for the common cold.
A randomized, controlled, double-masked clinical trial was conducted with a combination antiviral-antimediator treatment for experimental rhinovirus colds. In all, 150 healthy men and women (aged 18-51 years) were randomly assigned to 1 of 3 groups: intranasal interferon (IFN)-alpha2b (6 x 10(6) U every 12 h x 3) plus oral chlorpheniramine (12 mg extended release) and ibuprofen (400 mg) every 1...
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The common cold is a viral illness that affects persons of all ages, prompting frequent use of over-the-counter and prescription medications and alternative remedies. Treatment focuses on relieving symptoms (e.g., cough, nasal congestion, rhinorrhea). Dextromethorphan may be beneficial in adults with cough, but its effectiveness has not been demonstrated in children and adolescents. Codeine has...
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A dynamic capsid is critical to the events that shape the viral life cycle; events such as cell attachment, cell entry, and nucleic acid release demand a highly mobile viral surface. Protein mass mapping of the common cold virus, human rhinovirus 14 (HRV14), revealed both viral structural dynamics and the inhibition of such dynamics with an antiviral agent, WIN 52084. Viral capsid digestion fra...
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Rhinovirus infections have afflicted humanity since the dawn of civilization, and are difficult to treat even with modern medicine. Throughout the ages many remedies have been used for the common cold, often caused by the rhinovirus. Recent research points to a flavanol anti-oxidant, quercetin, as having therapeutic properties. Quercetin has been shown to reduce viral internalization and replic...
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BACKGROUND The common cold is one of the most widespread illnesses and is a leading cause of visits to the doctor and absenteeism from school and work. Trials conducted in high-income countries since 1984 investigating the role of zinc for the common cold symptoms have had mixed results. Inadequate treatment masking and reduced bioavailability of zinc from some formulations have been cited as i...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2002
ISSN: 1537-6613,0022-1899
DOI: 10.1086/341455